PUBLICATIONS

Selected Publications (1999 - present)

You, G.
Membrane Transporters in Drug Disposition
Pharmaceutical Research 2008, 25(2): 441-3
 
Zhou, F., Tanaka, K., and You, G.
Comparison of the Interaction of Human Organic Anion Transporter hOAT4 with PDZ Proteins between Kidney Cells and Placental Cells
Pharmaceutical Research 2008, 25(2):475-80
 
Zhou, F., Hong, M, and You, G.
Regulation of human organic anion transporter 4 (hOAT4) by progesterone and protein kinase C in human placental BeWo cells
American Journal of Physiology 2007, 293(1):E57-61
 
Hong, M., Zhou, F., and You, G. 
Analysis of transmembrane domain 7 of the Human Organic Anion Transporter hOAT1
Journal of Pharmacology and Experimental Therapeutics 2007, 320(3):1209-15
 
Hong, M., Tanaka, K., Pan, Z., Ma, J., and You, G.
Determination of the external loops and the cellular orientation of the amino- and the carboxyl termini of the human organic anion transporter hOAT1
Biochemical Journal, 2007, 401(2):515-20
 
Zhou, F., and You, G.
Molecular insights into the structure and function of organic anion transporters
Pharmaceutical Research 2007, 24(1):28-36
 
Xu, W., Tanaka, K., Sun, A., and You, G.
The functional role of C terminus of human organic anion transporter hOAT1 
Journal of Biological Chemistry 2006, 281:31178-83
 
Zhou, F., Illsley, N.P., and You, G. 
Functional characterization of a human organic anion transporter hOAT4 in placental BeWo cells. 
European Journal of Pharmaceutical Sciences 2006, 27(5):518-23

Hong, M., Xu, W., Yoshida, T., Tanaka, K., Zhou, F., Inouye, M., and You, G.
Human organic anion transporter hOAT1 forms homooligomers
Journal of Biological Chemistry 2005, 280(37):32285-90
 
Zhou, F., Xu, W., Hong, M., Pan, Z., Sinko, P.J., Ma, J., and You, G.
The role of N-linked glycosylation in protein folding, membrane targeting and substrate binding of human organic anion transporter hOAT4
Molecular Pharmacology 2005; 67(3):868-76
 
Hong, M., Zhou, F., and You, G. 
Critical amino acid residues in transmembrane domain 1 of the human organic anion transporter hOAT1. 
Journal of Biological Chemistry 2004, 279(30):31478-82
 
Zhou, F., Pan, Z., Ma, J., and You, G. 
Mutational analysis of histidine residues in the human organic anion transporter 4 
Biochemical Journal  2004, 384:87-92
 
You, G. 
Towards an understanding of organic anion transporters: structure-function relationships.
Medicinal Research Review 2004, 24:762-74
 
Zhou, F., Tanaka, K., Pan, Z., Ma, J., and You G. 
The role of glycine residues in the function of human organic anion transporter 4 (hOAT4). 
Molecular Pharmacology 2004; 65:1141-7.
 
Tanaka, K., Xu, W., Zhou, F., and You, G. 
Role of glycosylation in the organic anion transporter 1 (OAT1). 
Journal of Biological Chemistry 2004; 279:14961-6
 
You, G. 
The role of organic ion transporters in drug disposition: an update
Current Drug Metabolism 2004; 5:55-62.
 
Tanaka, K., Zhou, F., Kuze, K., and You, G. 
Cysteine residues in the organic anion transporter mOAT1
Biochemical Journal  2004; 380:283-287
Zhou, F., Tanaka, K., Soares,  M.J., and You G. 
Characterization of an organic anion transport system in a placental cell line
American Journal of Physiology  2003; 285(5):E1103-9.
 
You, G. 
Structure, function, and regulation of drug transporters OAT.
Medicinal Research Review 2002; 22(6):602-16.
 
You, G.
, Kuze, K., Kohanski, R. A., Amsler, K., and Handerson, S. 
Regulation of mOAT-mediated organic anion transport by okadaic acid and protein kinase C in LLC-PK1 cells
Journal of Biological Chemistry 2000; 275(14): 10278-10284.

Kuze, K., Greves, P., Leahy, A., Wilson, P., Stuhlmann, H., and You, G. 
Heterologous expression and functional characterization of a mouse renal organic anion
transporter in mammalian cells
Journal of Biological Chemistry 1999; 274(3): 1519-1524.



Books

You, G. and Morris, M. E.  (Editors)
DRUG TRANSPORTERS - Molecular Characterization and Role in Drug Disposition
Wiley Series in Drug Discovery and Development
Series Editor: Wang, B.




Department of Pharmaceutics, Ernest Mario School of Pharmacy
Rutgers, The State University of New Jersey
160-Frelinghuysen Road, Piscataway, NJ 08854-8022, USA.
Tel: (732) 445-3831 *218; Fax: (732) 445-3134

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Last Updated: 06/10/2008
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