Rutgers: Department of Pharmaceutics

Research Interests: Molecular and cellular pharmacology, drug/toxin elimination, transporters

Drug transporters mediate the absorption, distribution, and excretion of a diverse array of clinically important drugs, including anti-HIV therapeutics, anti-tumor drugs, antibiotics, anti-hypertensives, and anti-inflammatories, and therefore are critical to the survival of the mammalian species. The long term goal of Dr. You's research is to elucidate the molecular and functional characteristics of these transporters, their implications in human physiology and diseases, and their applications to drug therapy. Currently, her research focuses on 1) the structure and function relationships of these transporters, and 2) their short-term and long-term regulatory mechanisms. Techniques in molecular biology, biochemistry, and biophysics are used to analyze the transport mechanisms. The knowledge gained from these studies will have significant impact on the future design of strategies aimed at maximizing therapeutic efficacy and minimizing toxicity, and will permit insight into the molecular, cellular, and clinical bases of renal, hepatic, neurological and fetal toxicity and disease.

Research Research Interests Research Group Publications Patents Invited Talks Abstracts	Academics Education Awards Professional Experience Teaching Vitae
Others Calendar Links Open Positions Department Home Page	Can't read PDF files? Download free Adobe Acrobate Reader.

	Guofeng You, Ph.D. Professor Rutgers University Department of Pharmaceutics Ernest Mario School of Pharmacy William Levine Hall Piscataway, NJ, 08854 (732) 445-3831 x218 FAX - 3134 gyou@rci.rutgers.edu